Human Desoxypentose Nucleic Acid: Isolation of Desoxypentose Nucleic Acid from Human Sperm

Purine and Pyrimidine Contents of Some Desoxypentose Nucleic Acids

The distribution of purines and pyrimidines in desoxypentose nucleic acids prepared from a variety of animal and plant sources has been studied. 1. The nucleic acids were prepared from calf thymus, calf kidney, sheep spleen, horse spleen, chicken erythrocyte, turtle erythrocyte, trout sperm, shad testes, sea urchin sperm, wheat germ, and Pneumococcus Type III. 2. Separate hydrolyses were carrie...

Schneider W C. Phosphorus compounds in animal tissues. I. Extraction and estimation of desoxypentose nucleic acid and of pentose nucleic acid. J .Biol. Chem. 161: 293-303, 1945

“It is indeed most gratifying to learn 31 years after publishing my paper that it is one of the most cited scientific papers. It is not entirely surprising to me that this should be the case since methods are the backbone of all scientific research. Consequently, my method for the extraction of nucleic acids from tissues and for their analysis might be expected to be referred to more frequently...

Nucleic acid aptamers in human viral disease.

Nucleic acid aptamers are short, single-stranded oligonucleotides or their modified analogues which avidly and specifically interact with targeted ligands through their 3-dimensional structure. Aptamers can be selected out of a large combinatorial oligonucleotide library through an in vitro evolution process termed SELEX. Since 1990, a wide variety of aptamers targeted to ligands ranging from s...

Nucleic Acid Encoding Human REV1 Protein

Nucleic acid concentrations in normal human plasma.

Utilizing a simple, rapid, and inexpensive modification of a fluorometric method, we determined the normal concentrations of nucleic acids (DNA and RNA) in human blood plasma of healthy individuals. DNA concentrations (13.9 ± 3.7 mg/ liter) were in excellent agreement with those reported by other methods. However, the RNA concentrations (144 ± 22 mg/liter) we found were higher than previously r...